与许多花卉不同，宜昌的蜡梅多生长在石灰岩地质山区，无需特别养护便自然成长，悄然开花。这种坚韧的品性，使得古代文人墨客对其倾心有加。北宋政治家、文学家欧阳修被贬夷陵时，曾写下“未腊梅先发，经霜叶不凋”的诗句，描写蜡梅不畏寒冬、生机勃发的画面，赞颂生命力的顽强与美好。
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However, Koch never credited the Hesses for their discovery of bacteriological agar, perhaps because, at the time, he failed to recognize its importance. Even after he received the insight about agar from the Hesses, Koch stuck with gelatine for years. In 1883-84, during his first medical expedition to Egypt and India to investigate cholera, he tried and failed to grow the cholera bacterium on gelatine media in the hot climate of Cairo (despite using a half-open fridge for incubation), only succeeding in the colder winter of Calcutta.